CHEMISTRY NEWS
For the most up-to-date news from the Department of Chemistry.
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Recent News
PUBLICATION: "Polyphenols have unique cellular effects that are distinct from antioxidant function in Toll-like receptor 4-mediated inflammation in RAW264.7 macrophage-like cells"
Abstract
Plant polyphenols are bioactive compounds touted for their antioxidant effects, and this is often the primary attribute used to explain their health benefits. However, we hypothesize that polyphenols have molecular properties independent of antioxidant...read more ❯
Regents’ Professor Jenny J. Yang Represents Georgia State at World Business Angel Investment Forum
During the event, she was honored with the prestigious Disruptive Innovation Award, which recognizes the fastest-growing brands and acknowledges the founders, angel investors, crowd funders and early stage venture capital investors behind them.
read more ❯
Novel Cancer Treatment From Georgia State Research and Da Zen Theranostics Advances to Next Stage of Clinical Trials
The treatment illuminates tumor cells during surgery to improve quality of life, patient treatment and survival rates. read more ❯
PUBLICATION: "A Tale of Two Cities in Fluorescent Sensing of Carbon Monoxide: Probes That Detect CO and Those That Detect Only Chemically Reactive CO Donors (CORMs), but Not CO"
Abstract:
Carbon monoxide (CO) is endogenously produced with a range of pharmacological activities. Sensitive and selective detection of CO is critical to studying its biology. Since the first report of a CO fluorescent probe in 2012, more than 100 papers on this...read more ❯
PUBLICATION "Oligomerization of Protein Arginine Methyltransferase 1 and Its Functional Impact on Substrate Arginine Methylation"
Abstract
Protein arginine methyltransferases (PRMTs) are important post-translational modifying enzymes in eukaryotic proteins and regulate diverse pathways from gene transcription, RNA splicing, and signal transduction to metabolism. Increasing evidence supports...read more ❯
Dr. Chayan Dutta selected as a Scialog Fellow
Dear GSU Chem colleagues,
Please join me in congratulating Dr. Chayan Dutta for being selected as a Scialog Fellow in Neurobiology & Changing Ecosystems. If you want to learn more about Scialog, please visit...read more ❯
Dr. Suazette Mooring elected Councilor of the ACS-DivCHED
Dear GSU Chem Colleagues,
Please join me in congratulating Dr. Suazette Mooring for being elected to serve a three-year term as Councilor of the American Chemical Society Division of Chemical Education, one of the thirty-two technical divisions of the...read more ❯
NEW PUBLICATION: "Architectural organization and in situ fusion protein structure of lymphocytic choriomeningitis virus"
Abstract
Arenaviruses exist globally and can cause hemorrhagic fever and neurological diseases, exemplified by the zoonotic pathogen lymphocytic choriomeningitis virus (LCMV). The structures of individual LCMV proteins or their fragments have been reported, but...read more ❯
NEW PUBLICATION: "A Highly Atom-Efficient Prodrug Approach to Generate Synergy between H2S and Nonsteroidal Anti-inflammatory Drugs and Improve Safety"
Abstract
Efforts to synergize hydrogen sulfide (H2S) with NSAIDs have faced challenges due to complex structural entities and independent release kinetics. This study presents a highly atom-efficient approach of using a thiocarboxylic acid (thioacid) as a novel...read more ❯
NEW PUBLICATION: "Single GC base pair recognition by a heterocyclic diamidine: structures, affinities, and dynamics"
Abstract
The recognition of specific genomic arrangements by rationally designed small molecules is fundamental for the expansion of targeted gene expression. Here, we report the first X-ray crystal structures that demonstrate single G (guanine) recognition by a...read more ❯
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Giovanni Gadda
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Maged Henary
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Suazette Mooring
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Samer Gozem
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