Instruction and Services
Instruments and Services: The MS Facilities is well equipped to do mass spectrometric analysis of macromolecules such as proteins, peptides, oligonucleotides, lipids, and carbohydrates and small molecules with separation capabilities using chromatographic techniques such as GC, LC.
|Mass Spectrometers||Ionization||Mass Analyzer||Application|
|Q-TOF micro (Waters Micromass)||ESI APCI||Quadruple-TOF||Nominal mass measurements
Accurate mass measurements (5 ppm)
Elemental composition analyses
Tandem mass measurements
|UltrafleXtreme-MALDI TOF-TOF-Imaging||MALDI||TOF-TOF||Mass determinations of intact proteins, peptides, oligonuclotides, glycolipids, carbohydrates and other small organic molecules
Protein identification and characterization
Protein post-translational modification characterization
Peptide de novo sequencing
Protein quantitative analysis
MALDI imaging biomarker discovery and identification
|ESI APCI||Triple Quadruple||Nominal mass measurements
Tandem mass measurements
Liquid chromatographic separations
|EI, NCI, PCI||Single Quadruple||Nominal mass measurements
Gas chromatographic separations
The Bruker Daltonics ultrafleXtreme MALD TOF-TOF-Tissue Imaging
The UltrafleXtreme MALDI TOF-TOF is a proteomics analyzer that utilizes tandem TOF technology and Proteinscape software to provide high-throughput protein and biomarker identification and discovery with high confidence.
The Waters Micromass Q-Tof micro Mass Spectrometer
The Micromass Q-Tof micro mass spectrometer coupled with Waters 2695 HPLC can provide both routine structural elucidation of small molecules and biomacromolecules as well as exact mass measurements with both Electrospray Ionization (ESI) and Atmospheric Pressure Chemical Ionization (APCI) techniques. The instrument also features a quadruple mass filter and collision cell for MS/MS analyses and is equipped with a Waters Alliance HPLC and an nanoAcquity UPLC for separation.
API 3200 LC/MS/MS System
The API 3200 LC/MS/MS system is a triple quadruple mass spectrometer coupled with an Agilent 1200 series HPLC and UV-DAD used ideally for qualitative and quantitative analysis of chemical and biological molecules (M/Z < 1800 Da).
More information on this instrument.
The Shimadzu GCMS QP-5050 Aquadrupole GC/MS System
This instrument has both electron ionization (EI) and chemical ionization (positive CI and negative CI) capabilities with high sensitivities. A mixture can be separated by gas chromatography and analyzed by a single quadruple analyzer.