(78) Shenghui Xue, Jingjuan Qiao, Jie Jiang, Lixia Wei, Shuanyi Li, Kendra Hubbard, Zhiren Liu, Jenny J. Yang. Design Protein-based MRI Contrast Agent with High Dose Efficiency and Capability for Molecular Imaging of Biomarkers. Medical Research Review , (2010). Under Review.

(77) Shen Tang, Hing-Cheung Wong, Zhong-Ming Wang, Yun Huang, Jin Zou, You Zhuo, Andrea Pennati, Giovanni Gadda, Osvaldo Delbono, Jenny Yang. Proc Natl Acad Sci, (2011) Sep 27;108(39):16265-70

(76) Yanyi Chen, Yubin Zhou, Lin Xianming, Hing-Cheung Wong, Qin Xu, Jie Jiang, Siming Wang, Charles F. Louis, Richard Veenstra, and Jenny J. Yang. Molecular interaction and functional regulation of connexin50 gap junction by calmodulin. Biochemical Journal (2011).May 1; 435(3):711-22

(75). Jinjuan Qiao, Shunyi Li,Jie Jiang, Lixia Wei, Robert Liang, Liyia Wang, Hui Mao, Hua Yang, Hans Grossniklaus, Zhiren Liu and Jenny J. Yang. HER-2 Targeted Molecular MR Imaging Using a de vovo Designed Protein Contrast Agent. PLoS ONE (2011). Mar 24;6(3):e18103

(74). Jie Jiang, Yubin Zhou, Jin Zou, Yanyi Chen, Pryia Patel, Jenny J. Yang, and Edward Balog, Site-specific modification of calmodulin Ca(2+) affinity tunes the skeletal muscle ryanodine receptor activation profile, Biochemical Journal (2010), Nov 15;432(1):89-99.

(73). Yun Huang, Yubin Zhou, Adriana Castiblanco, Hing-Cheung Wong, Yangyi Chen, Edward M. Brown, and Jenny J. Yang. Calmodulin Regulates Calcium-Sensing Receptor-mediated Ca 2+ Signaling and its Cell Surface Expression. Journal of Biological Chemistry. (2010). 285 (46):35919-31. Epub 2010 Sep 8.

(72). Yusheng Jiang, Yun Huang, Hing Wong, Yubin Zhou, Xue Wang, Jenny J. Yang, Randy Hall, and Edward Brown, Elucidation of a novel extracellular calcium binding site on metabotropic glutamate receptor 1α (mGluR1α) that controls receptor activation, Journal of Biological Chemistry (2010), Oct 22; 285(43):33463-74.

(71). Xue Wang, Kun Zhao, Michael Kirberger, Hing Wong, Guantao Chen, and Jenny J.Yang, Analysis and prediction of calcium-binding pockets from apo-protein structures exhibiting calcium-induced localized conformational changes, Protein Science (2010), 19(6): 1180-90.

(70). Lixia Wei, Shunyi Li, Jianhua Yang, Yimin Ye, Jin Zou, Liya Wang, Robert Long, Omar Zurkiya, Tiejun Zhao, Julian Johnson, Jingjuan Qiao, Wangda Zhou, Adriana Castiblanco, Natalie Maor, Yanyi Chen, Hui Mao, Xiaoping Hu, Jenny J. Yang, Zhi-Ren Liu, Protein-Based MRI Contrast Agents for Molecular Imaging of Prostate Cancer (2010), Molecular Imaging and Biology, In Press.

(69). Yubin Zhou, Wen-Pin Tzeng, Hing-Cheung Wong, Yiming Ye, Jie Jiang, Yanyi Chen, Yun Huang, Suganthi Suppiah, Teryl K. Frey, and Jenny J. Yang, Calcium-dependent association of calmodulin with the rubella virus nonstructural protease domain, Journal of Biological Chemistry (2010), 285(12): 8855-68.

(68). Anna Wilkins Maniccia, Wei Yang, Julian A Johnson, Shunyi Li, Harianto Tjong, Huan-Xiang Zhou, Lev A Shaket, and Jenny J Yang, Inverse tuning of metal binding affinity and protein stability by altering charged coordination residues in designed calcium binding proteins, PMC Biophysics (2009) 21(2): 11

(67) Yanyi Chen, Shenghui Xue, Yubin Zhou,Jenny J. Yang. Calciomics: Prediction and Analysis of EF-hand Calcium-binding Proteins by Protein Engineering. Science China (2010).Jan 1; 53 (1):52-60

(66). Michael Kirberger, Xue Wang, Kun Zhao, Shen Tang, Guantao Chen, and Jenny J.Yang, Integration of diverse research methods to analyze and engineerCa(2+)-binding proteins: From prediction to production, Current Bioinformatics (2010), 5(1): 68-80.

(65). Haizhen Wang, Xueliang Gao, Yun Huang, Jenny Yang, and Zhi-Ren Liu, P68 RNA helicase is a nucleocytoplasmic shuttling protein, Cell Research (2009), 19(12): 1388-1400

(64). Ning Chen, Yun Huang, Lily Yang, Rihe Liu, and Jenny J. Yang, Designing Caspase-3 Sensors for Imaging of Apoptosis in Living Cells. Chemistry - A European Journal (2009), 15(37): 9311-9314.

(63). Yun Huang, Yubin Zhou, Hing-Cheung Wong, Yanyi Chen, Yan Chen, Siming Wang, Adriana Castiblanco, Aimin Liu, and Jenny J. Yang, A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca(2+), FEBS Journal (2009), 276(19): 5589-97.

(62). Yubin Zhou, Teryl K. Frey, and Jenny J. Yang, Viral calciomics: Interplays between Ca(2+) and virus. Cell Calcium, 2009, 46(1): 1-17.

(61). Ning Chen, Ye Yimin, Jin Zou, Shunyi Li, Amy Martin, Robert Wohlhueter, and Jenny J. Yang, Fluorescence complementation via EF-hand interactions. Journal of Biotechnology (2009), 142(3-4): 205-213.

(60). Angela Holder, April L. Ellis, Jin Zou, Ning Chen, and Jenny J. Yang Facilitating chromophore formation of engineered Ca(2+) binding green fluorescent proteins. Arch Biochem Biophys (2009), 486(1): 27-34.

(59). Ning Chen, Jin Zou, Siming Wang, Yiming Ye, Yun Huang, Giovanni Gadda, and Jenny J. Yang, Designing Protease Sensors for Real-Time Imaging of Trypsin Activation in Pancreatic Cancer Cells. Biochemistry (2009), 48(15): 3519-3526.

(58). Yubin Zhou, Wei Yang, Monica Lurtz, Ning Chen, Jie Jiang, Yun Huang, Charles Louis, and Jenny J. Yang, Calmodulin mediates the Ca(2+)-dependent regulation of Cx44 gap junctions. Biophysical Journal (2009), 96(7): 2832-2848.

(57). Yun Huang, Yubin Zhou, Adriana Castiblanco, Wei Yang, Edward M. Brown, and Jenny J. Yang, Multiple Ca(2+)-binding sites in the extracellular domain of the Ca(2+)-sensing receptor corresponding to cooperative Ca(2+) response. Biochemistry (2009), 48(2): 787-798.

(56). Yubin Zhou, Wen-Pin Tzeng, Yun Huang, Yiming Ye, Yanyi Chen, Teryl K. Frey and Jenny J. Yang. A Cysteine-rich Metal-binding Domain from Rubella Virus Nonstructural Protein is Essential for Viral Protease Activity and Virus Replication. Biochemical Journal (2009) 417 (2):477-83. PMID: 18795894.

(55). Xue Wang, Michael Kirberger, Guantao Chen , and Jenny J. Yang , Towards Predicting Ca 2+ –binding Sites with Different Coordination Numbers in Proteins with Atomic Resolution, Proteins (2009), 75(4): 1099-1107.

(54). Shunyi Li, Wei Yang, Anna Wilkins Mannicia, Doyle Barrow Jr., Harianto Tjong, Huan-Xiang Zhou, and Jenny Yang, Rational Design of Switchable Calcium and Lanthanide Binding Proteins. FEBS (2008), 275(20): 5048-5061.

(53). Michael Kirberger, Xue Wang, Hai Deng,Wei Yang, Guantao Chen, and Jenny J Yang Statistical Analysis of Structural Characteristics of Protein Ca(2+)-binding sites. Journal Biological Inorganic Chemistry (2008), 130(29): 9260-9267.

(52). Michael Kirberger and Jenny J. Yang, Structural Differences Between Pb(2+)- and Ca(2+)-binding Sites in Proteins: Implications with Respect to Toxicity. Journal of Inorganic Biochemistry (2008), 102(10): 1901-1909.

(51). Jenny J. Yang, Jianhua Yang, Lixia Wei, Wei Yang, Omar Zurkiya, Hui Mao, Fuqian Zhao, Russell Malchow, Shunyi Li, Anna L. Wilkins Mannicia, Shumin Zhao, Jin Zou, Julian Johnson, Xiaoping Hu, Eirk Krogstad, and Zhi-Ren Liu, Rational Design Protein Based MRI Contrast Agents with High Relaxivity Journal of the American Chemical Society (2008), 130(29):9260-7.

(50). Lisa Jones, Wei Yang, Anna L. Wilkins Mannicia, Alice Kearney, Anton P. van der Merwe, and Jenny J. Yang. Rational Design of a novel calcium binding site adjacent to the ligand binding site on CD2 increases its CD48 affinity. Protein Science (2008) . 17(3): 439-49.

(49) Yubin Zhou, Wei Yang, Monica Lurtz, Yiming Ye, Yun Huang, Hsiau-wei Lee, Yanyi Chen, Charles Louis, and Jenny Yang. Identification of the Calmodulin Binding Domain of Connexin43. Journal of Biological Chemistry (2007), 282(48): 35005-17.

(48) Yubin Zhou, Wen-Pin Tzeng, Wei Yang, Yumei Zhou, Yiming Ye, Hsiau-wei Lee, Teryl K. Frey, and Jenny Yang. Identification of a Ca2+-Binding Domain in the Rubella Virus Nonstructural Protease. Journal of Virology (2007), 81, 7517-28.

(47) Yun Huang, Yubin Zhou, Wei Yang, Robert Butters, Hsiau-Wei Lee, Shunyi Li, Adriana Castiblanco, Edward M Brown, and Jenny J Yang. Identification and Dissection of Ca2+-Binding Sites in the Extracellular Domain of Ca 2+ -sesing Receptor. Journal of biological chemistry (2007), 282, 19000-10.

(46). Yanling Zhang, Minyong Li, Sekar Chandrasekaran, Xingming Gao, Xikui Fang, Hsiau-wei Lee, Kenneth Hardcastle, Jenny Yang, and Binghe Wang. A Unique Quinolineboric Acid-based Supramolecular Structure that Relies on Double Intermolecular B-N Bonds for Self-assembly in Solid State and in Solution. Tetrahedron (2007). 63 :3287-92.

(45) Jin Zou, Aldebaran M. Hofer, Monica M. Lurtz, Giovanni Gadda, April L. Ellis, Ning Chen, Yun Huang, Angela Holder, Yiming Ye, Charles F. Louis, Kristy Welshhans, Vincent Rehder, and Jenny J. Yang. Developing Sensors for Real-Time Measurement of High Ca2+ Concentrations. Biochemistry (2007), 46, 12275-12288.

(44). Jenny J. Yang, Roland Pochet, and Arthur S. Nolen. Calcium, Diversity and Evolution, Meeting Report of Calcium Binding Proteins in Normal and Transformed Cells and Diseases. Calcium Binding Protein (2006); 1 (3), 170-174.

(43).Yuan Liu, Qiao Tong, Yubin Zhou, Hsiau-Wei Lee, Jenny J. Yang, Hans-Jörg Bühring, Yi-Tien Chen, Binh Ha, Celia X.-J. Chen and Ke Zen. Functional Elements on SIRPa IgV Domain Mediate Cell Surface Binding to CD47 Journal of Molecular Biology (2006) 365 (3):680-93. Epub 2006 Oct 3.

(42) Jenny J. Yang. Calmodulin, the Suprises Continue. Calcium Binding Protein (2006), 1, 65-66.

(41) Yubin Zhou, Wei Yang, Michael Kirberger, Hsiau-Wei Lee, Gayatri Ayalasomayajula, and Jenny J. Yang. Prediction of EF-hand Calcium Binding Proteins and Analysis of Bacterial EF-hand Proteins. Proteins (2006),Nov 15;65(3):643-55.

(40) Anna Wilkins Maniccia, Wei Yang, Shunyi Li, Julian A. Johnson, Jenny J Yang. using Protein design to dissect the effect of charged residues on metal binding and protein stability. Biochemistry (2006), 45, 5848-5856.

(39) Hai Deng, Guantao Chen, Wei Yang, Jenny J. Yang. Predicting calcium-binding sites in proteins - a graph theory and geometry approach. Proteins (2006), 64, 34-42.

(38). Chunru Lin, Liuqing Yang, Jenny J. Yang, Youliang Huang, and Zhi-Ren Liu. ATPase/Helicase Activities of p68 RNA Helicase are Required for Pre-mRNA Splicing but not for Assembly of the Spliceosome. Molecular and Cellular Biology (2005). 25 (17) 7484-7493.

(37) Wei Yang, Anna L. Wilkins, Shunyi Li, Yiming Ye, Jenny J. Yang. The effects of Ca2+ binding on the dynamic properties of a designed Ca2+-binding protein. Biochemistry (2005), 44, 8267-8273.

(36) Jin Zou, Yiming Ye, Kristy Welshhans, Monica Lurtz, April L Ellis, Charles Louis, Vincent Rehder, and Jenny J Yang. Expression and Optical Properties of Green Gluorenscent Protein Expressed in Different Cellular Environments. Journal of Biotechology (2005), 119, 368-378.

(35) Yiming Ye, Hsiau-Wei Lee, Wei Yang, and Jenny J Yang. Calcium and Lanthanide Affinity of the EF-loops from the C-terminal of Calmodulin. Journal of Inorganic Biochemistry (2005), 99, 1376-1383.

(34) Amy R. Carroll, Wei Yang, Yiming Ye, and Jenny Jie Yang. Amyloid Fibril Formation in a Domain of Rat Cell Adhesion Molecule. Cell Biochemistry and Biophysics (2006), 44, 241-249.

(33) Yiming Ye, Sarah Shealy, Hsiau-Wei Lee, Wei Yang, and Jenny J. Yang. Probing site-specific metal binding affinity of EF-hand Proteins by Grafting. Journal of the American Chemical Society (2005), 127, 3743-3750.

(32) Yang W, Wilkins AL, Ye YM, Liu ZR, Li SY, Urbauer JL, Hellinga HW, Kearney A, van der Merwe PA and Yang JJ, Design of a calcium-binding protein with desired structure in a cell adhesion molecule. Journal of the American Chemical Society (2005), 127, 2085-2093.