Publications in the last five years:
Tsai, K-C.; Wang, S-H.; Hsiao, N-W.; Li, M.; Wang, B. “The Effect of Different Electrostatic Potentials on Docking Accuracy: A Case Study using DOCK5.4” Bioorg. Med. Chem. Lett., 2008, manuscript in preparation.
Ko, K-C.; Kamio, M.; Zheng, S.; Wang, B. Collins, S.; Gadda, G.; Tai, P-C.; Derby, C. “The Chemistry of Escapin: Identification and Quantification of the Products of an L-Amino Acid Oxidase in the Defensive Secretion of the Sea Snail Aplysia californica, Under Natural Conditions” Chem. Biol., 2008, manuscript in preparation.
Yin, C.; Hui, X.; Xu, P.; Niu, L.; Wang, B. “A Highly Efficient and Direct Approach for Asymmetric Synthesis of (E)-2-Arylidene-1,4-diphenylbut-3-yn-1-amines by Addition of Alkynylzinc to Chiral N-tert-Butansulfinyl Imines” J. Am. Chem. Soc., 2008, manuscript in preparation.
Ni, N.; Choudhary, G.; Li, M.; Wang, B. “Pyrogallol and its analogs can antagonize bacterial quorum sensing in Vibrio harveyi” Bioorg. Med. Chem. Lett., 2008, manuscript accepted.
Ni, N.; Li, M.; Wang, J.; Wang, B. “Inhibitors of Bacterial Quorum Sensing” Med. Res. Rev., 2008, manuscript in preparation.
Shan, J.; Cheng, Y.F.; Reid, S.; Wang, B. “Carbohydrate Recognition and Sensing” Sensors, 2008, invited manuscript in preparation..
Ni, N.T.; Chou, H.-T.; Wang, J.F.; Lu, C.-D.; Wang, B. “Identification of Boronic Acids as Antagonists of Bacterial Quorum Sensing in Vibrio harveyi” Bioorg. Med. Chem. Lett., 2008, manuscript in preparation.
Li, M.; Ni, N.; Wang, B. Zhang, Y. “Modeling the Excitation Wavelengths (lambda ex) of Boronic Acids” J. Mol. Model., 2008, manuscript accepted.
Li, M.; Huang, Y-J.; Tai, P.C.; Wang, B. “Discovery of the First SecA Inhibitors Using Structure-Based Virtual Screening” Biochem. Biophys. Res. Commun., 2008, manuscript accepted.
Li, M.; Huang, Z.; Lin, N.; Wang, S.; Altier, C.; Wang, B. “Going after the "Sweet Spot" in Selecting Aptamer for a Glycoprotein” Angew. Chem. Int. Ed., 2008, manuscript in revision.
Zheng, S.; Kaur, G.; Wang, H.; Li, M.; Macnaughtan, M.; Reid, S.; Yang, X.; Wang, B. Ke, H.; Prestgard, J. “Synthesis, SAR, Molecular Modeling, and NMR Studies of Phenylalkyl Ketone Series as Highly Potent and Selective PDE4D Inhibitors” J. Med. Chem., 2008, manuscript submitted.
Jin, S.; Li, M.; Zhu, C.; Tran, V.; Wang, B. “Computer-based De Novo Design, Synthesis, and Evaluation of Boronic Acid-based Artificial Receptors for Selective Recognition of Dopamine” ChemBiochem, 2008, manuscript accepted pending revision.
Jin, S.; Wang, J.; Li, M.; Wang, B. “Synthesis, Evaluation, and Computational Studies of Naphthalimide-based Long-wavelength Fluorescent Boronic Acid Reporters” Chem. Eur. J., 2008, manuscript in press
Akay, S.; Yang, W.; Wang, J.; Lin, L.; Wang, B. “Synthesis of Dual Fluorescent Benzo[b]thiophene Boronic Acid Derivatives for Sugar Sensing” Chem. Biol. Drug. Design, 2007, 70, 279-289.
Wang, J.; Jin, S.; Akay, S.; Wang, B. “Design and synthesis of a long-wavelength fluorescent boronic acid reporter compound” Eur. J. Org. Chem., 2007, 2091-2099.
Zhang, Y.; Li, M.; Chandrasekaran, S.; Gao, X.; Fang, X. Lee, H-W.; Hardcastle, K.; Yang, J.; Wang, B. “A unique quinolineboronic acid-based supramolecular structure that relies on double intermolecular B-N bonds for self-assembly in solid state and in solution” Tetrahedron, 2007, 63, 3287-3292.
Zheng, S.; Lin, N.; Reid, S. Wang, B. “Effect of extended conjugation with a phenylethynyl group on the fluorescent properties of water-soluble arylboronic acids” Tetrahedron, 2007, 63, 5427-5436.
Li, M.; Wang, B. “Homology Modeling and the Examination of the Effect of the D92E Mutation on the H5N1 Nonstructural Protein NS1 Effector Domain” J. Comp. Model., 2007, 13, 237-1244.
Fang, H.; Kaur, G.; Wang, B. “Functional Group Approaches to Prodrugs: Functional Groups in Peptides” in Prodrugs: Challenges and Rewards,, Editors: V.J. Stella, R.T. Borchardt, M.J. Hageman, R. Oliyai, and J. Tilley, Vol 4 in “Biotechnology: Pharmaceutical Aspects”, Series Editors: R. T. Borchardt and C. R. Middaugh AAPS Press, 2007.
Zheng, S.; Wang, B. “Iodomethyl Methyl Ether 13057-19-7” Encycl. Reagen. Org. Syn, 2007, DOI: 10.1002/047084289X.ri030.pub2.
Lin, N.; Yan, J.; Huang, Z.; Altier, C.; Yan, J. Carrasco, N.; Suyemoto, M.; Johnson, L.; Fang, H.; Wang, Q.; Wang, S.; Wang, B. “Design and synthesis of boronic acid-modified thymidine triphosphate for incorporation into DNA” Nucl. Acid Res., 2007, 35, 1222-1229.
Jin, B. Zhang, Y.; Wang, B. “Granular Kernel Trees with Parallel Genetic Algorithms for Drug Activity Comparisons” Int. J. Data Mining Bioinform, 2007, 1, 270-285.
Zhang, Y.; Ballard, C.E.; Zheng, S.; Gao, X.; Ko, K.C.; Yang, H.; Brandt, G.; Lou, X.; Tai, P.C.; Lu, C-D.; Wang, B. “Design, synthesis and evaluation of efflux substrate-metal chelator conjugates as potential anti-microbial agents” Bioorg. Med. Chem. Lett., 2007, 17, 707-711.
Zhang, Y.; Gao, X.; Hardcastle, K.; Wang, B. “Water-soluble Fluorescent Boronic Acid Compounds for Saccharide Sensing: Structural Effect on Their Fluorescence Properties” Chem.-Eur. J., 2006, 12, 1377-1384.
Zou, W.; He, M; Yue, P.; Zhou, Z.; Lin, N.; Lonial, S.; Khuri, F.R.; Wang, B.; Sun, S-Y. “Vitamin C Inactivates the Proteasome Inhibitor PS-341 (Bortezomib) in Human Cancer Cells” Clin. Cancer Res., 2006, 12, 273-280 (Editorial Clin. Cancer Res. 2006, 12, 3-4).
Wang, J.; Lin, N.; Jin, S.; Wang, B. “Indolylboronic acids Fluorescent Reporters for Sugar Sensing and Recognition” Chem. Biol. Drug Design, 2006, 67, 137-144.
Kaur, G.; Fang, H.; Gao, X.; Li, H.; Wang, B. “Diboronic Glucose Sensors” Tetrahedron, 2006 , 62, 2583-2589.
Zheng, S.; Reid, S.; Lin, N.; Wang, B. “Microwave-assisted Synthesis of Ethynylarylboronates for the Construction of Boronic acid-based Fluorescent Sensors for Carbohydrates” Tetrahedron Lett., 2006, 47, 2331-2335.
Kaur, G.; Lin, N.; Fang, H.; Wang, B. “Boronic Acid-based Glucose Sensors” in Topics in Fluorescence Spectroscopy, vol. 11, “Glucose Sensing”, Geddes, C.D. and Lakowicz, J.R., Editors, Springer Press, 2006 , pp 377-397.
Li, M.; Wang, B. “Computational Studies of H5N1 Hemagglutinin Binding with SA-α-2, 3-Gal and SA-α-2, 6-Gal” Biochem. Biophys. Res. Commun., 2006, 347, 662-668.
Yang, W.; Gao, S.; Wang, B. “Biologically Active Boronic Acid Compounds” in Organoboronic Acids, Hall, D., Ed., Wiley-VCH, 2005, 481-512.
Fang, H.; Kaur, G.; Yan, J.; Wang, B. “An Efficient Synthesis of Sterically Hindered Arylboronic Acids” Tetrahedron Lett. 2005, 46, 1671-1674.
Gao, X.; Zhang, Y.; Wang, B. “Naphthalene-based Water-soluble Fluorescent Sensors for Saccharides at Physiological pH” N. J. Chem. 2005, 29, 579-586.
Han, C.; Wang, B. “Factors that Impact the Developability of Drug Candidates-An Overview” in Delivery Issues in Drug Discovery, Editors: B. Wang, T. Siahaan, R. Soltero, John Wiley and Sons, 2005 , 1-15.
Wang, W.; Gao, S.; Wang, B. “Molecularly Imprinted Polymers As Recognition Elements In Optical Sensors” in Molecularly Imprinted Materials: Science and Technology, Mingdi Yan and Olof Ramstrom, eds., Marcel Dekker, 2005 , 701-726.
Chen X.; Yang, W.; Sivamani, E.; Bruneau, A.H.; Wang, B.; and Qu, R. “Elimination of Perennial Ryegrass by Engineering E. coli argE gene and suicidal activation of Pro-herbicide, N-acetyl-PPT” Mol. Breeding 2005, 15, 339-347.
Fang, H.; Yan, J.; Wang, B. “Boronolectins and Fluorescent Boronolectins-An Examination of the Detailed Chemistry Issues Important for their Design” Med. Res. Rev. 2005 , 25, 490-520.
Gao, X.; Zhang, Y.; Wang, B. “A Highly Fluorescent Water-soluble Naphthalene-based Boronic Acid Reporter for Saccharide Sensing that also Shows Ratiometric UV Changes” Tetrahedron, 2005 , 61, 9111-9117.
Wang, J.; Jin, S.; Wang, B. “A New Boronic Acid Fluorescent Reporter that Changes Emission Intensity at Three Wavelengths upon Sugar Binding” Tetrahedron Lett. 2005 , 46, 7003-7006.
Yang, W.; Lin, L.; Wang, B. “A Novel Type of Fluorescent Boronic Acid for Carbohydrate Recognition” Tetrahedron Lett. 2005 , 46, 7981-7984.
Yan, J.; Jin S.; Wang, B. “A Novel Redox-Sensitive Protecting Group for Boronic Acids, MPMP-Diol” Tetrahedron Lett. 2005 , 46, 8503-8505.
Wang, J.; Lin, N.; Jin, S.; Wang, B. “Indolylboronic acids Fluorescent Reporters for Sugar Sensing and Recognition” Chem. Biol. Drug Design, 2005, manuscript accepted pending minor revisions.
Ni, W.; Fang, H.; Springsteen, G.; Wang, B. “Design of Boronic Acid Spectroscopic Reporter Compounds by Taking Advantage of the pKa-Lowering Effect of Diol-binding: Nitrophenol-based Color Reporters for Diols” J. Org. Chem. 2004, 69, 1999-2007.
Fang, H.; Yan, J.; Wang, B. “Biaryl Product Formation from Cross-coupling in Palladium-Catalyzed Borylation of a Boc Protected Aminoquinoline Compound” Molecules, 2004, 2, 178-184.
Zych, L.; Yang, W.; Griffin, K.; Liao, Y.; Wang, B. “Coumarin-based Cyclic Prodrugs of Peptides-The Effect of Substitution” Bioorg. Chem. 2004, 32, 109-123.
Fang, H.; Li, J.; Sun, Y.; Wang, B.; Zhang, Y.-Q. “A New Ddata Mining Tool for Analyzing Coumarin-based Prodrugs,” Proc. of SPIE”™s Defence & Security 2004: Conference on Data Mining and Knowledge Discovery: Theory, Tools, and Technology, 2004,5433, 142-152.
Fang, H.; Kaur, G.; Wang, B. “Progress in Boronic Acid-Based Fluorescent Glucose Sensors” J. Fluorescence, 2004 , 14 , 481-489.
Yang, W.; Fan, H.; Gao, S.; Gao, X.; Ni, W.; Karnati, V.; Hooks, W.B.; Carson, J.; Weston, B.; Wang, B. “The First Fluorescent Diboronic Acid Sensor Specific for Hepatocellular Carcinoma Cells Expressing Sialyl Lewis X” Chem. Biol. 2004, 11, 439-448.
Yan, J.; Springsteen, G.; Deeter, S.; Wang, B. “The Relationship among pKa, pH, and Binding Constants in the Interactions between Boronic Acids and Diols-It is not as Simple as It Appears” Tetrahedron, 2004 , 60, 11205-11209.
Yang, W.; Lin, L.; Wang, B. “A New Type of Water-Soluble Fluorescent Boronic Acid Suitable for Construction of Polyboronic Acids for Carbohydrate Recognition” Heterocycl. Commun. 2004 , 10, 383-388.
Ni, W.; Kaur, G.; Springsteen, G.; Wang, B.; Franzen, S. “Regulating the Fluorescence Intensity of an Anthracene Boronic Acid System: A B-N Bond or a Hydrolysis Mechanism?” Bioorg. Chem. 2004 , 32, 571-581.
Wang, W.; Zheng, A.; Liu, S.; Wang, B. “Solid Supports, Linkers and Solid-Phase Supported Reagents in Chemical Library Synthesis” in Combinatorial Approaches to Drug Lead Discovery, Liu, G.; Xiao, X.; Wang, J. Eds. p88-122, Science Press, New York, 2003.
Yang, W.; Gao, S.; Wang, B. “Boronic Acid Compounds as Potential Pharmaceutical Agents” Med. Res. Rev. 2003, 23, 346-368.
Yang, W.; Yan, J.; Springsteen, G.; Deeter, S.; and Binghe Wang “A Novel Type of Fluorescent Boronic Acid that Shows Large Fluorescence Intensity Changes upon Binding with a Diol in Aqueous Solution at Physiological pH” Bioorg. Med. Chem. Lett. 2003, 13, 1019 - 1022.
Yang, W.; Yan, J.; Fang, H.; Wang, B. “The First Fluorescent Sensor for D-Glucarate Based on the Cooperative Action of Boronic Acid and Guanidinium Groups” Chem. Commun. 2003, 792 - 793 .
Franzen, S.; Ni, W.; Wang, B. “A Study of the Mechanism of Electron Transfer Quenching by Boron-Nitrogen Adducts in Fluorescent Sensors” J. Phys. Chem. B 2003, 107, 12942-12948.
Gao, X.; Zhang, Y.; Wang, B. “New Boronic Acid Fluorescent Reporter Compounds II. A Naphthalene-based Sensor Functional at Physiological pH” Org. Lett. 2003 , 5, 4615-4618.
Ballard, C.E.; Yu, H.; Wang, B. “Recent Development in Depsipeptide Research” Current Med. Chem. 2002, 9, 471-498.
Springsteen, G. and Wang, B. “A Detailed Examination of Boronic Acid-Diol Complexation” Tetrahedron 2002, 58, 5291-5300.
Yang, W.; Gao, S.; Gao, X.; Karnati, V.R.; Ni, W.; Wang, B.; Hooks, W.B.; Carson, J.; Weston, B. “Diboronic Acids as Fluorescent Probes for Cells Expressing Sialyl Lewis X” Bioorg. Med. Chem. Lett. 2002, 12, 2175-2177.
Yang, W.; Gao, X.; Springsteen, G.; Wang, B. “Catechol Pendant Polystyrene for Solid Phase Synthesis” Tetrahedron Lett. 2002, 43, 6339-6342.
Wang, W.; Gao, X. and Wang, B. “Boronic Acid-based Sensors for Carbohydrates” Current Organic Chemistry, 2002, 6, 1285-1317.
Yu, H.; Ballard, C.E.; Boyle, P.; Wang, B. “Highly Diastereoselective Synthesis of α-Hydroxycarboxylic Acids Using Fructose-derived Chiral Auxiliaries” Tetrahedron, 2002, 58, 7663-7679.
Liu, S.; Han, C.; Wang, B. “Prodrug Derivatization as a Means to Enhance the Delivery of Peptide and Peptidomimetic Drugs” in Frontiers of Biotechnology and Pharmaceuticals, Ming Guo, ed, Science Press, New York, 2002, p291-310.
Han, C.; Liu, S.; Wang, B. “Major Factors Influencing Peptide Drug Absorption” in Frontiers of Biotechnology and Pharmaceuticals, Ming Guo, ed, Science Press, New York, 2002, p270-290.
Karnati, V.; Gao, X.; Gao, S.; Yang, W.; Sabapathy, S.; Ni, W.; Wang, B. “A Selective Fluorescent Sensor for Glucose” Bioorg. Med. Chem. Lett. 2002, 12, 3373-3377.
Gao, S.; Wang, W.; Wang, B. "A OsO4-Mediated Carbon-Carbon Bond Cleavage Reaction to Give Anthraquinone" Chem. Lett. 2001, 48-49.
Yu, H.; Wang, B. "Phenylboronic Acids Facilitated Selective Reduction of Aldehydes by Tributyltin Hydride" Synthetic Commun. 2001, 31, 163-169.
Yu, H.; Ballard, C.E.; Wang, B. “Highly Diastereoselective Ester Enolate Alkylation Using a Fructose-Derived Chiral Auxiliary for the Synthesis of α-Hydroxycarboxylic Acids” Tetrahedron Lett. 2001, 42, 1835-1838.
Gao, S.; Herzig, D.; Wang, B. "A Novel One-Step Conversion of Primary Amines to Nitriles" Synthesis 2001, 544-546.
Latta, R.P.; Springsteen, G.; Wang, B. "Development of an Arylboronic Acid-based Solid-Phase Amidation Catalyst" Synthesis 2001, 1611-1613.
Springsteen, G.; Ballard, C.E.; Gao, S.; Wang, W.; Wang, B. “The Development of Photometric Sensors for Boronic Acids” Bioorg. Chem., 2001, 29, 259-270.
Springsteen, G.; Wang, B. “Alizarin Red as a General Fluorescent Reporter for Studying the Binding of Boronic Acids and Carbohydrates” Chem. Commun. 2001, 1608-1609.
Gao, S.; Wang, W.; Wang, B. “Building Fluorescent Sensors for Carbohydrates Using Template-directed Polymerizations.” Bioorg. Chem. 2001, 29, 308-320.
Jiang, J.; Wang, W.; Sane, D.; Wang, B. "Synthesis of New RGD Analogs for Targeted Drug Delivery" Bioorg. Chem. 2001, 29, 357-379.