College of Arts & Sciences

Recent Publications

Recent publications of the Chemistry Department via PubMed

Quaye, Osbourne; Nguyen, Tranbao; Gannavaram, Swathi; Pennati, Andrea; Gadda, Giovanni. "Rescuing of the Hydride Transfer Reaction in the Glu312asp Variant of Choline Oxidase by a Substrate Analogue." Arch. Biochem. Biophys., 2010, 499, 1-5.

Spencer, Sarah M; Lin, Lina; Chiang, Cheng-Feng; Peng, Zhengchun; Hesketh, Peter; Salon, Jozef; Huang, Zhen. "Direct and Rapid Detection of Rnas on a Novel Rna Microchip." Chembiochem : a European journal of chemical biology, 2010, 11, 1378-1382.

Xin, Yao; Doshi, Urmi; Hamelberg, Donald. "Examining the Limits of Time Reweighting and Kramers' Rate Theory to Obtain Correct Kinetics from Accelerated Molecular Dynamics." J Chem Phys, 2010, 132, 224101.

Feng, Jingyu; Liu, Juan; Wu, Baohua; Wang, Gangli. "Impedance Characteristics of Amine Modified Single Glass Nanopores." Anal. Chem., 2010, 82, 4520-8.

Branowska, Danuta; Farahat, Abdelbasset A; Kumar, Arvind; Wenzler, Tanja; Brun, Reto; Liu, Yang; Wilson, W David; Boykin, David W. "Synthesis and Antiprotozoal Activity of 2,5-bis[amidinoaryl]thiazoles." Bioorg. Med. Chem., 2010, 18, 3551-8.

Finnegan, Steffan; Agniswamy, Johnson; Weber, Irene T; Gadda, Giovanni. "Role of Valine 464 in the Flavin Oxidation Reaction Catalyzed by Choline Oxidase." Biochemistry, 2010, 49, 2952-61.

Sheng, Jia; Huang, Zhen. "Selenium Derivatization of Nucleic Acids for X-ray Crystal-structure and Function Studies." Chem. Biodivers., 2010, 7, 753-85.

Gu, Congying; Shamsi, Shahab A. "Cec-atmospheric Pressure Ionization Ms of Pesticides Using a Surfactant-bound Monolithic Column." Electrophoresis, 2010, 31, 1162-74.

Rungsrisuriyachai, Kunchala; Gadda, Giovanni. "Role of Asparagine 510 in the Relative Timing of Substrate Bond Cleavages in the Reaction Catalyzed by Choline Oxidase." Biochemistry, 2010, 49, 2483-90.

Zhou, Yubin; Tzeng, Wen-Pin; Wong, Hing-Cheung; Ye, Yiming; Jiang, Jie; Chen, Yanyi; Huang, Yun; Suppiah, Suganthi; Frey, Teryl K; Yang, Jenny J. "Calcium-dependent Association of Calmodulin with the Rubella Virus Nonstructural Protease Domain." J. Biol. Chem., 2010, 285, 8855-68.

Raux, Elizabeth; Klenc, Jeffrey; Blake, Ava; Saczewski, Jarosław; Strekowski, Lucjan. "Conjugate Addition of Nucleophiles to the Vinyl Function of -chloro--vinylpyrimidine Derivatives." Molecules, 2010, 15, 1973-84.

Tang, Zhenghua; Xu, Bin; Wu, Baohua; Germann, Markus W; Wang, Gangli. "Synthesis and Structural Determination of Multidentate 2,3-Dithiol-Stabilized Au Clusters." J. Am. Chem. Soc., 2010, 132, 3367-74.

Allison, Stuart A; Pei, Hongxia; Baek, Saerom; Brown, Jocelyn; Lee, Min Y; Nguyen, Vu; Twahir, Umar T; Wu, Hengfu. "The Dependence of the Electrophoretic Mobility of Small Organic Ions on Ionic Strength and Complex Formation." Electrophoresis, 2010, 31, 920-32.

Jin, Shan; Cheng, Yunfeng; Reid, Suazette; Li, Minyong; Wang, Binghe. "Carbohydrate Recognition by Boronolectins, Small Molecules, and Lectins." Med Res Rev, 2010, 30, 171-257.

Kelley, Jennifer Munro; Hamelberg, Donald. "Atomistic Basis for the On-Off Signaling Mechanism in Sam-II Riboswitch." Nucleic Acids Res., 2010, 38, 1392-400.

Hassan, Abdalla E A; Sheng, Jia; Zhang, Wen; Huang, Zhen. "High Fidelity of Base Pairing by 2-Selenothymidine in DNA." J. Am. Chem. Soc., 2010, 132, 2120-1.

Du, Lupei; Ni, Nanting; Li, Minyong; Wang, Binghe. "A Fluorescent Hydrogen Peroxide Probe Based on a 'click' Modified Coumarin Fluorophore." Tetrahedron letters, 2010, 51, 1152-1154.

Yang, Xiaochuan; Dai, Chaofeng; Molina, Angie Dayan Calderon; Wang, Binghe. "Boronic Acid-modified DNA That Changes Fluorescent Properties Upon Carbohydrate Binding." Chem. Commun. (Camb.), 2010, 46, 1073-5.

Jin, Shan; Zhu, Chunyuan; Cheng, Yunfeng; Li, Minyong; Wang, Binghe. "Synthesis and Carbohydrate Binding Studies of Fluorescent alpha-Amidoboronic Acids and the Corresponding Bisboronic Acids." Bioorg. Med. Chem., 2010, 18, 1449-55.

Chen, Weixuan; Huang, Ying-ju; Gundala, Sushma Reddy; Yang, Hsiuchin; Li, Minyong; Tai, Phang C; Wang, Binghe. "The First Low Microm Seca Inhibitors." Bioorg. Med. Chem., 2010, 18, 1617-25.

Salon, Jozef; Sheng, Jia; Gan, Jianhua; Huang, Zhen. "Synthesis and Crystal Structure of 2'-Se-Modified Guanosine Containing DNA." J. Org. Chem., 2010, 75, 637-41.

Gu, Congying; He, Jun; Jia, Jinping; Fang, Nenghu; Simmons, Robert; Shamsi, Shahab A. "Surfactant-bound Monolithic Columns for Separation of Proteins in Capillary High Performance Liquid Chromatography." J Chromatogr A, 2010, 1217, 530-9.

Farahat, Abdelbasset A; Kumar, Arvind; Say, Martial; Barghash, Alaa El-Din M; Goda, Fatma E; Eisa, Hassan M; Wenzler, Tanja; Brun, Reto; Liu, Yang; Mickelson, Leah; Wilson, W David; Boykin, David W. "Synthesis, Dna Binding, Fluorescence Measurements and Antiparasitic Activity of Dapi Related Diamidines." Bioorg. Med. Chem., 2010, 18, 557-66.

Gadda, Giovanni; Francis, Kevin. "Nitronate Monooxygenase, a Model for Anionic Flavin Semiquinone Intermediates in Oxidative Catalysis." Arch. Biochem. Biophys., 2010, 493, 53-61.

Liu, Yang; Wilson, W David. "Quantitative Analysis of Small Molecule-nucleic Acid Interactions with a Biosensor Surface and Surface Plasmon Resonance Detection." Methods Mol. Biol., 2010, 613, 1-23.

Doshi, Urmi; Hamelberg, Donald. "Reoptimization of the Amber Force Field Parameters for Peptide Bond (omega) Torsions Using Accelerated Molecular Dynamics." J Phys Chem B, 2009, 113, 16590-5.

Maniccia, Anna Wilkins; Yang, Wei; Johnson, Julian A; Li, Shunyi; Tjong, Harianto; Zhou, Huan-Xiang; Shaket, Lev A; Yang, Jenny J. "Inverse Tuning of Metal Binding Affinity and Protein Stability by Altering Charged Coordination Residues in Designed Calcium Binding Proteins." PMC Biophys, 2009, 2, 11.

Fu, Rong; Liu, Fange; Davidson, Victor L; Liu, Aimin. "Heme Iron Nitrosyl Complex of Maug Reveals an Efficient Redox Equilibrium Between Hemes with Only One Heme Exclusively Binding Exogenous Ligands." Biochemistry, 2009, 48, 11603-5.

Collar, Catharine J; Al-Salabi, Mohammed I; Stewart, Mhairi L; Barrett, Michael P; Wilson, W David; de Koning, Harry P. "Predictive Computational Models of Substrate Binding by a Nucleoside Transporter." J. Biol. Chem., 2009, 284, 34028-35.

Pennati, Andrea; Gadda, Giovanni. "Involvement of Ionizable Groups in Catalysis of Human Liver Glycolate Oxidase." J. Biol. Chem., 2009, 284, 31214-22.

Gu, Congying; He, Jun; Jia, Jinping; Fang, Nenghu; Shamsi, Shahab A. "Surfactant-bound Monolithic Columns for Cec." Electrophoresis, 2009, 30, 3814-27.

Zhang, Xinjian; Dou, Jun; Germann, Markus W. "Characterization of the Cellular Immune Response in Hepatitis C Virus Infection." Med Res Rev, 2009, 29, 843-66.

Nguyen, Binh; Wilson, W David. "The Effects of Hairpin Loops on Ligand-dna Interactions." The Journal of Physical Chemistry. B, 2009, 113, 14329-35.

Mishra, Subrata H; Spring, Alexander M; Germann, Markus W. "Thermodynamic Profiling of HIV Rreiib RNA-Zinc Finger Interactions." J. Mol. Biol., 2009, 393, 369-82.

Allison, Stuart A; Pei, Hongxia; Baek, Saerom; Garcia, Jennifer N; Lee, Min Y; Nguyen, Vu; Twahir, Umar T. "Viscosity of Dilute Model Bead Arrays at Low Shear: Inclusion of Short Range Solute-solvent Interactions." The Journal of Physical Chemistry. B, 2009, 113, 13576-84.

Xin, Yao; Gadda, Giovanni; Hamelberg, Donald. "The Cluster of Hydrophobic Residues Controls the Entrance to the Active Site of Choline Oxidase." Biochemistry, 2009, 48, 9599-605.

Sheng, Jia; Hassan, Abdalla E A; Huang, Zhen. "Synthesis of the First Tellurium-derivatized Oligonucleotides for Structural and Functional Studies." Chemistry, 2009, 15, 10210-6.

Francis, Kevin; Gadda, Giovanni. "Kinetic Evidence for an Anion Binding Pocket in the Active Site of Nitronate Monooxygenase." Bioorg. Chem., 2009, 37, 167-72.

Liu, Zong-Ying; Wang, Yue-Ming; Li, Zhuo-Rong; Jiang, Jian-Dong; Boykin, David W. "Synthesis and Anticancer Activity of Novel 3,4-diarylthiazol-2(3H)-ones (imines)." Bioorg. Med. Chem. Lett., 2009, 19, 5661-4.

Huang, Yun; Zhou, Yubin; Wong, Hing-Cheung; Chen, Yanyi; Chen, Yan; Wang, Siming; Castiblanco, Adriana; Liu, Aimin; Yang, Jenny J. "A Single EF-hand Isolated from Stim1 Forms Dimer in the Absence and Presence of Ca²⁺." FEBS J., 2009, 276, 5589-97.

Jin, Shan; Choudhary, Gaurav; Cheng, Yunfeng; Dai, Chaofeng; Li, Minyong; Wang, Binghe. "Fluoride Protects Boronic Acids in the Copper(I)-mediated Click Reaction." Chem. Commun. (Camb.), 2009, 5251-3.

Chen, Ning; Huang, Yun; Yang, Lily; Liu, Rihe; Yang, Jenny J. "Designing Caspase-3 Sensors for Imaging of Apoptosis in Living Cells." Chemistry, 2009, 15, 9311-4.

Hu, Laixing; Arafa, Reem K; Ismail, Mohamed A; Patel, Alpa; Munde, Manoj; Wilson, W David; Wenzler, Tanja; Brun, Reto; Boykin, David W. "Synthesis and Activity of Azaterphenyl Diamidines Against Trypanosoma Brucei Rhodesiense and Plasmodium Falciparum." Bioorg. Med. Chem., 2009, 17, 6651-8.

Quaye, Osbourne; Gadda, Giovanni. "Effect of a Conservative Mutation of an Active Site Residue Involved in Substrate Binding on the Hydride Tunneling Reaction Catalyzed by Choline Oxidase." Arch. Biochem. Biophys., 2009, 489, 10-4.

Peng, Hanjing; Cheng, Yunfeng; Ni, Nanting; Li, Minyong; Choudhary, Gaurav; Chou, Han Ting; Lu, Chung-Dar; Tai, Phang C; Wang, Binghe. "Synthesis and Evaluation of New Antagonists of Bacterial Quorum Sensing in Vibrio Harveyi." ChemMedChem, 2009, 4, 1457-68.

Tevis, Denise S; Kumar, Arvind; Stephens, Chad E; Boykin, David W; Wilson, W David. "Large, Sequence-dependent Effects on DNA Conformation by Minor Groove Binding Compounds." Nucleic Acids Res., 2009, 37, 5550-8.

Hu, Laixing; Kully, Maureen L; Boykin, David W; Abood, Norman. "Synthesis and Structure-activity Relationship of Dicationic Diaryl Ethers As Novel Potent Anti-mrsa and Anti-vre Agents." Bioorg. Med. Chem. Lett., 2009, 19, 4626-9.

Wang, Bin; He, Jun; Bianchi, Victoria; Shamsi, Shahab A. "Combined Use of Chiral Ionic Liquid and Cd for Mekc: Part Ii. Determination of Binding Constants." Electrophoresis, 2009, 30, 2820-8.

Wang, Bin; He, Jun; Bianchi, Victoria; Shamsi, Shahab A. "Combined Use of Chiral Ionic Liquid and Cyclodextrin for Mekc: Part I. Simultaneous Enantioseparation of Anionic Profens." Electrophoresis, 2009, 30, 2812-9.

Chen, Ning; Ye, Yiming; Zou, Jin; Li, Shunyi; Wang, Siming; Martin, Amy; Wohlhueter, Robert; Yang, Jenny J. "Fluorescence Complementation Via EF-hand Interactions." J. Biotechnol., 2009, 142, 205-13.

Pei, Hongxia; Germann, Markus W; Allison, Stuart A. "Translational Diffusion Constants of Short Peptides: Measurement by NMR and Their Use in Structural Studies of Peptides." The Journal of Physical Chemistry. B, 2009, 113, 9326-9.

Abou-Elkhair, Reham A I; Dixon, Dabney W; Netzel, Thomas L. "Synthesis and Electrochemical Evaluation of Conjugates Between 2'-deoxyadenosine and Modified Anthraquinone: Probes for Hole-transfer Studies in DNA." J. Org. Chem., 2009, 74, 4712-9.

Hu, Laixing; Kully, Maureen L; Boykin, David W; Abood, Norman. "Optimization of the Central Linker of Dicationic Bis-benzimidazole Anti-mrsa and Anti-vre Agents." Bioorg. Med. Chem. Lett., 2009, 19, 3374-7.

Zhou, Yubin; Frey, Teryl K; Yang, Jenny J. "Viral Calciomics: Interplays Between Ca²⁺ and Virus." Cell Calcium, 2009, 46, 1-17.

Ni, Nanting; Choudhary, Gaurav; Peng, Hanjing; Li, Minyong; Chou, Han-Ting; Lu, Chung-Dar; Gilbert, Eric S; Wang, Binghe. "Inhibition of Quorum Sensing in Vibrio Harveyi by Boronic Acids." Chemical biology & drug design, 2009, 74, 51-6.

Hassan, Abdalla E A; Sheng, Jia; Jiang, Jiansheng; Zhang, Wen; Huang, Zhen. "Synthesis and Crystallographic Analysis of 5-se-thymidine DNAs." Org. Lett., 2009, 11, 2503-6.

Allison, Stuart A; Pei, Hongxia. "Viscosity of Dilute Suspensions of Rigid Bead Arrays at Low Shear: Accounting for the Variation in Hydrodynamic Stress over the Bead Surfaces." The journal of physical chemistry. B, 2009, 113, 8056-65.

Athri, Prashanth; Wilson, W David. "Molecular Dynamics of Water-mediated Interactions of a Linear Benzimidazole-biphenyl Diamidine with the DNA Minor Groove." J. Am. Chem. Soc., 2009, 131, 7618-25.

Holder, Angela N; Ellis, April L; Zou, Jin; Chen, Ning; Yang, Jenny J. "Facilitating Chromophore Formation of Engineered Ca(2+) Binding Green Fluorescent Proteins." Arch. Biochem. Biophys., 2009, 486, 27-34.

He, Jun; Shamsi, Shahab A. "Multivariate Approach for the Enantioselective Analysis in Mekc-ms: Ii. Optimization of 1,1'-binaphthyl-2,2'-diamine in Positive Ion Mode." Journal of separation science, 2009, 32, 1916-26.

Burch, C P; Chandrasekaran, S; Henary, M M; Spring, A; Strekowski, L; Smith, J C. "An Investigation of the Interaction of Iminosulfurane Transdermal Penetration Enhancers with Model Skin Preparations Using NMR Spectroscopy." International journal of pharmaceutics, 2009, 373, 48-54.

Ni, Nanting; Choudhary, Gaurav; Li, Minyong; Wang, Binghe. "A New Phenothiazine Structural Scaffold As Inhibitors of Bacterial Quorum Sensing in Vibrio Harveyi." Biochem. Biophys. Res. Commun., 2009, 382, 153-6.

Chen, Ning; Zou, Jin; Wang, Siming; Ye, Yiming; Huang, Yun; Gadda, Giovanni; Yang, Jenny J. "Designing Protease Sensors for Real-time Imaging of Trypsin Activation in Pancreatic Cancer Cells." Biochemistry, 2009, 48, 3519-26.

Zhou, Yubin; Yang, Wei; Lurtz, Monica M; Chen, Yanyi; Jiang, Jie; Huang, Yun; Louis, Charles F; Yang, Jenny J. "Calmodulin Mediates the Ca²⁺-dependent Regulation of Cx44 Gap Junctions." Biophys. J., 2009, 96, 2832-48.

Jin, Shan; Zhu, Chunyuan; Li, Minyong; Wang, Binghe. "Identification of the First Fluorescent Alpha-amidoboronic Acids That Change Fluorescent Properties Upon Sugar Binding." Bioorg. Med. Chem. Lett., 2009, 19, 1596-9.

Pei, Hongxia; Allison, Stuart. "The Free Solution Electrophoretic Mobility of Peptides by a Bead Modeling Methodology." J Chromatogr A, 2009, 1216, 1908-16.

Pei, Hongxia; Allison, Stuart; Haynes, Bridgette M H; Augustin, Daphne. "Brownian Dynamics Simulation of the Diffusion of Rods and Wormlike Chains in a Gel Modeled As a Cubic Lattice: Application to DNA (dagger)." The Journal of Physical Chemistry. B, 2009, 113, 2564-71.

Rungsrisuriyachai, Kunchala; Gadda, Giovanni. "A Ph Switch Affects the Steady-state Kinetic Mechanism of Pyranose 2-oxidase from Trametes Ochracea." Arch. Biochem. Biophys., 2009, 483, 10-5.

Hu, Laixing; Kully, Maureen L; Boykin, David W; Abood, Norman. "Synthesis and in Vitro Activity of Dicationic Bis-benzimidazoles As a New Class of Anti-mrsa and Anti-vre Agents." Bioorg. Med. Chem. Lett., 2009, 19, 1292-5.

Rahimian, Maryam; Kumar, Arvind; Say, Martial; Bakunov, Stanislav A; Boykin, David W; Tidwell, Richard R; Wilson, W David. "Minor Groove Binding Compounds That Jump a Gc Base Pair and Bind to Adjacent At Base Pair Sites." Biochemistry, 2009, 48, 1573-83.

Feng, You; Xie, Nan; Wu, Jiang; Yang, Chao; Zheng, Yujun George. "Inhibitory Study of Protein Arginine Methyltransferase 1 Using a Fluorescent Approach." Biochem. Biophys. Res. Commun., 2009, 379, 567-72.

Xie, Nan; Elangwe, Emilia N; Asher, Sabrina; Zheng, Yujun George. "A Dual-mode Fluorescence Strategy for Screening Hat Modulators." Bioconjug. Chem., 2009, 20, 360-6.

Wu, Jiang; Xie, Nan; Wu, Zhikun; Zhang, Ying; Zheng, Yujun George. "Bisubstrate Inhibitors of the Myst Hats Esa1 and Tip60." Bioorg. Med. Chem., 2009, 17, 1381-6.

He, Jun; Shamsi, Shahab A. "Multivariate Approach for the Enantioselective Analysis in Micellar Electrokinetic Chromatography-mass Spectrometry I. Simultaneous Optimization of Binaphthyl Derivatives in Negative Ion Mode." Journal of Chromatography. A, 2009, 1216, 845-56.

Zheng, Jie; Bragg, William; Hou, Jingguo; Lin, Na; Chandrasekaran, Sekar; Shamsi, Shahab A. "Sulfated and Sulfonated Polysaccharide As Chiral Stationary Phases for Capillary Electrochromatography and Capillary Electrochromatography-mass Spectrometry." Journal of Chromatography. A, 2009, 1216, 857-72.

Nguyen, Binh; Neidle, Stephen; Wilson, W David. "A Role for Water Molecules in DNA-ligand Minor Groove Recognition." Acc. Chem. Res., 2009, 42, 11-21.

Huang, Yun; Zhou, Yubin; Castiblanco, Adriana; Yang, Wei; Brown, Edward M; Yang, Jenny J. "Multiple Ca²⁺-binding Sites in the Extracellular Domain of the Ca²⁺-sensing Receptor Corresponding to Cooperative Ca²⁺ Response." Biochemistry, 2009, 48, 388-98.

Zhou, Yubin; Tzeng, Wen-Pin; Ye, Yiming; Huang, Yun; Li, Shunyi; Chen, Yanyi; Frey, Teryl K; Yang, Jenny J. "A Cysteine-rich Metal-binding Domain from Rubella Virus Non-structural Protein is Essential for Viral Protease Activity and Virus Replication." Biochem. J., 2009, 417, 477-83.

Hamelberg, Donald; McCammon, J Andrew. "Mechanistic Insight into the Role of Transition-state Stabilization in Cyclophilin A." J. Am. Chem. Soc., 2009, 131, 147-52.

Ni, Nanting; Li, Minyong; Wang, Junfeng; Wang, Binghe. "Inhibitors and Antagonists of Bacterial Quorum Sensing." Med Res Rev, 2009, 29, 65-124.

Lin, Lina; Sheng, Jia; Momin, Razin K; Du, Quan; Huang, Zhen. "Facile Synthesis and Anti-tumor Cell Activity of Se-containing Nucleosides." Nucleosides Nucleotides Nucleic Acids, 2009, 28, 56-66.

Finnegan, Steffan; Gadda, Giovanni. "Substitution of an Active Site Valine Uncovers a Kinetically Slow Equilibrium Between Competent and Incompetent Forms of Choline Oxidase." Biochemistry, 2008, 47, 13850-61.

Zheng, Shilong; Kaur, Gurpreet; Wang, Huanchen; Li, Minyong; Macnaughtan, Megan; Yang, Xiaochuan; Reid, Suazette; Prestegard, James; Wang, Binghe; Ke, Hengming. "Design, Synthesis, and Structure-activity Relationship, Molecular Modeling, and NMR Studies of a Series of Phenyl Alkyl Ketones As Highly Potent and Selective Phosphodiesterase-4 Inhibitors." J. Med. Chem., 2008, 51, 7673-88.

Arafa, Reem K; Ismail, Mohamed A; Munde, Manoj; Wilson, W David; Wenzler, Tanja; Brun, Reto; Boykin, David W. "Novel Linear Triaryl Guanidines, N-substituted Guanidines and Potential Prodrugs As Antiprotozoal Agents." European Journal of Medicinal Chemistry, 2008, 43, 2901-8.

Salon, Jozef; Jiang, Jiansheng; Sheng, Jia; Gerlits, Oksana O; Huang, Zhen. "Derivatization of DNAs with Selenium at 6-position of Guanine for Function and Crystal Structure Studies." Nucleic Acids Res., 2008, 36, 7009-18.

Wilson, Beth; Fernández, María-José; Lorente, Antonio; Grant, Kathryn B. "Synthesis and DNA Interactions of a Bis-phenothiazinium Photosensitizer." Org. Biomol. Chem., 2008, 6, 4026-35.

Bragg, William; Norton, Dean; Shamsi, Shahab A. "Optimized Separation of Beta-blockers with Multiple Chiral Centers Using Capillary Electrochromatography-mass Spectrometry." J. Chromatogr. B Analyt. Technol. Biomed. Life Sci., 2008, 875, 304-16.

Kovalevsky, Andrey Y; Ghosh, Arun K; Weber, Irene T. "Solution Kinetics Measurements Suggest Hiv-1 Protease Has Two Binding Sites for Darunavir and Amprenavir." J. Med. Chem., 2008, 51, 6599-603.

Hu, Laixing; Li, Zhuo-rong; Jiang, Jian-dong; Boykin, David W. "Novel Diaryl or Heterocyclic Sulfonamides As Antimitotic Agents." Anti-Cancer Agents in Medicinal Chemistry, 2008, 8, 739-45.

Li, Shunyi; Yang, Wei; Maniccia, Anna W; Barrow, Doyle; Tjong, Harianto; Zhou, Huan-Xiang; Yang, Jenny J. "Rational Design of a Conformation-switchable Ca²⁺- and Tb³⁺-binding Protein Without the Use of Multiple Coupled Metal-binding Sites." FEBS J., 2008, 275, 5048-61.

Kirberger, Michael; Yang, Jenny J. "Structural Differences Between Pb2+- and Ca2+-binding Sites in Proteins: Implications with Respect to Toxicity." J. Inorg. Biochem., 2008, 102, 1901-9.

Li, Minyong; Fang, Hao; Du, Lupei; Xia, Lin; Wang, Binghe. "Computational Studies of the Binding Site of Alpha1a-adrenoceptor Antagonists." Journal of Molecular Modeling, 2008, 14, 957-66.

Li, Minyong; Lin, Na; Huang, Zhen; Du, Lupei; Altier, Craig; Fang, Hao; Wang, Binghe. "Selecting Aptamers for a Glycoprotein Through the Incorporation of the Boronic Acid Moiety." J. Am. Chem. Soc., 2008, 130, 12636-8.

Francis, Kevin; Gadda, Giovanni. "The Nonoxidative Conversion of Nitroethane to Ethylnitronate in Neurospora Crassa 2-nitropropane Dioxygenase is Catalyzed by Histidine 196." Biochemistry, 2008, 47, 9136-44.

Wu, Jiang; Zheng, Yujun George. "Fluorescent Reporters of the Histone Acetyltransferase." Anal. Biochem., 2008, 380, 106-10.

Kirberger, Michael; Wang, Xue; Deng, Hai; Yang, Wei; Chen, Guantao; Yang, Jenny J. "Statistical Analysis of Structural Characteristics of Protein Ca²⁺-binding Sites." J. Biol. Inorg. Chem., 2008, 13, 1169-81.

Zheng, Yujun George; Wu, Jiang; Chen, Ziyue; Goodman, Masha. "Chemical Regulation of Epigenetic Modifications: Opportunities for New Cancer Therapy." Med Res Rev, 2008, 28, 645-87.

Li, Minyong; Ni, Nanting; Chou, Han-Ting; Lu, Chung-Dar; Tai, Phang C; Wang, Binghe. "Structure-based Discovery and Experimental Verification of Novel Ai-2 Quorum Sensing Inhibitors Against Vibrio Harveyi." ChemMedChem, 2008, 3, 1242-9.

Rahimian, Maryam; Miao, Yi; Wilson, W David. "Influence of DNA Structure on Adjacent Site Cooperative Binding." The journal of Physical Chemistry. B, 2008, 112, 8770-8.

Yang, Jenny J; Yang, Jianhua; Wei, Lixia; Zurkiya, Omar; Yang, Wei; Li, Shunyi; Zou, Jin; Zhou, Yubin; Maniccia, Anna L Wilkins; Mao, Hui; Zhao, Fuqiang; Malchow, Russell; Zhao, Shumin; Johnson, Julian; Hu, Xiaoping; Krogstad, Eirik; Liu, Zhi-Ren. "Rational Design of Protein-based Mri Contrast Agents." J. Am. Chem. Soc., 2008, 130, 9260-7.

Rungsrisuriyachai, Kunchala; Gadda, Giovanni. "On the Role of Histidine 351 in the Reaction of Alcohol Oxidation Catalyzed by Choline Oxidase." Biochemistry, 2008, 47, 6762-9.

Wilson, W David; Tanious, Farial A; Mathis, Amanda; Tevis, Denise; Hall, James Edwin; Boykin, David W. "Antiparasitic Compounds That Target DNA." Biochimie, 2008, 90, 999-1014.

Jin, Shan; Li, Minyong; Zhu, Chunyuan; Tran, ViLinh; Wang, Binghe. "Computer-based De Novo Design, Synthesis, and Evaluation of Boronic Acid-based Artificial Receptors for Selective Recognition of Dopamine." Chembiochem, 2008, 9, 1431-8.

Li, Minyong; Ni, Nanting; Wang, Binghe; Zhang, Yanqing. "Modeling the Excitation Wavelengths (lambda(ex)) of Boronic Acids." Journal of Molecular Modeling, 2008, 14, 441-9.

Sheng, Jia; Hassan, Abdalla E A; Huang, Zhen. "New Telluride-mediated Elimination for Novel Synthesis of 2',3'-didehydro-2',3'-dideoxynucleosides." J. Org. Chem., 2008, 73, 3725-9.

Allison, Stuart; Pei, Hongxia; Haynes, Margaret; Xin, Yao; Law, Lydia; Labrum, Josh; Augustin, Daphne. "Translational Diffusion of Macromolecules and Nanoparticles Modeled As Non-overlapping Bead Arrays in an Effective Medium." The journal of Physical Chemistry. B, 2008, 112, 5858-66.

Du, Li, Zheng, Wang,. "Rational Design of a Fluorescent Hydrogen Peroxide Probe Based on the Umbelliferone Fluorophore." Tetrahedron Lett., 2008, 49, 3045-3048.

Ni, Nanting; Chou, Han-Ting; Wang, Junfeng; Li, Minyong; Lu, Chung-Dar; Tai, Phang C; Wang, Binghe. "Identification of Boronic Acids As Antagonists of Bacterial Quorum Sensing in Vibrio Harveyi." Biochem. Biophys. Res. Commun., 2008, 369, 590-4.

Mijatovic, Slavica; Gadda, Giovanni. "Oxidation of Alkyl Nitronates Catalyzed by 2-nitropropane Dioxygenase from Hansenula Mrakii." Arch. Biochem. Biophys., 2008, 473, 61-8.

Li, Minyong; Huang, Ying-Ju; Tai, Phang C; Wang, Binghe. "Discovery of the First Seca Inhibitors Using Structure-based Virtual Screening." Biochem. Biophys. Res. Commun., 2008, 368, 839-45.

Miao, Yi; Cui, Tengjiao; Leng, Fenfei; Wilson, W David. "Inhibition of High-mobility-group A2 Protein Binding to DNA by Netropsin: a Biosensor-surface Plasmon Resonance Assay." Anal. Biochem., 2008, 374, 7-15.

Ni, Nanting; Choudhary, Gaurav; Li, Minyong; Wang, Binghe. "Pyrogallol and Its Analogs Can Antagonize Bacterial Quorum Sensing in Vibrio Harveyi." Bioorg. Med. Chem. Lett., 2008, 18, 1567-72.

Caton-Williams, Julianne; Huang, Zhen. "Biochemistry of Selenium-derivatized Naturally Occurring and Unnatural Nucleic Acids." Chem. Biodivers., 2008, 5, 396-407.

Jones, Lisa M; Yang, Wei; Maniccia, Anna W; Harrison, Alice; van der Merwe, P Anton; Yang, Jenny J. "Rational Design of a Novel Calcium-binding Site Adjacent to the Ligand-binding Site on Cd2 Increases Its Cd48 Affinity." Protein Sci., 2008, 17, 439-49.

Sook, Brian R; Block, Darci R; Sumithran, Suganya; Montañez, Griselle E; Rodgers, Kenton R; Dawson, John H; Eichenbaum, Zehava; Dixon, Dabney W. "Characterization of Siaa, a Streptococcal Heme-binding Protein Associated with a Heme Abc Transport System." Biochemistry, 2008, 47, 2678-88.

Pei, Hongxia; Xin, Yao; Allison, Stuart A. "Using Electrophoretic Mobility and Bead Modeling to Characterize the Charge and Secondary Structure of Peptides." Journal of Separation Science, 2008, 31, 555-64.

Ismail, Mohamed A; Arafa, Reem K; Wenzler, Tanja; Brun, Reto; Tanious, Farial A; Wilson, W David; Boykin, David W. "Synthesis and Antiprotozoal Activity of Novel Bis-benzamidino Imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines." Bioorg. Med. Chem., 2008, 16, 683-91.

Quaye, Osbourne; Lountos, George T; Fan, Fan; Orville, Allen M; Gadda, Giovanni. "Role of Glu312 in Binding and Positioning of the Substrate for the Hydride Transfer Reaction in Choline Oxidase." Biochemistry, 2008, 47, 243-56.

Caton-Williams, Julianne; Huang, Zhen. "Synthesis and DNA-polymerase Incorporation of Colored 4-selenothymidine Triphosphate for Polymerase Recognition and DNA Visualization." Angew. Chem. Int. Ed. Engl., 2008, 47, 1723-5.

Hu, Laixing; Arafa, Reem K; Ismail, Mohamed A; Wenzler, Tanja; Brun, Reto; Munde, Manoj; Wilson, W David; Nzimiro, Sandra; Samyesudhas, Serene; Werbovetz, Karl A; Boykin, David W. "Azaterphenyl Diamidines As Antileishmanial Agents." Bioorg. Med. Chem. Lett., 2008, 18, 247-51.

Rahmathullah, Syed M; Tidwell, Richard R; Jones, Susan K; Hall, James E; Boykin, David W. "Carbamate Prodrugs of N-alkylfuramidines." European journal of Medicinal Chemistry, 2008, 43, 174-7.

Tanious, Farial A; Nguyen, Binh; Wilson, W David. "Biosensor-surface Plasmon Resonance Methods for Quantitative Analysis of Biomolecular Interactions." Methods Cell Biol., 2008, 84, 53-77.