College of Arts & Sciences

Gangli Wang

Gangli Wang Assistant Professor Analytical Chemistry B.S. (1996):  Peking University, China M.S. (1999) :  Peking University, China Ph.D. (2004) :  University of North Carolina Postdoctoral Research Fellow (2004-2007) :  University of Utah Dr. Gangli Wang Department of Chemistry Georgia State University P.O. Box 4098 Atlanta, Georgia 30302-4098 Department Office Phone: 404-413-5500 Hours: M-F 9am - 5:30pm Phone:  404-413-5507 Lab Phone:  404-413-5523 Fax:  404-413-5505 Office:  420 Natural Science Center Email:  glwang@gsu.edu

Group Page

Research Projects

Single Bioactivity Sensing by Functional Nanopore Platforms

Ionic transport processes through nanoscale pores or pipettes, which generate current signals, are determined by the physical dimension of the device as well as localized ionic distribution at the conductance-limiting region, mostly the smallest opening. The current signal is modulated by the transport and binding of analyte of interest via either size blockage or local conductivity changes, or both. Foundational in nanomachinary assisted drug delivery, early diagnosis, and fundamental mechanism studies, the transport of individual nanoparticles and the binding of individual biomolecules are studied at single molecule single activity resolution.

Ionic transport at confined nanoscale interface - energy technology

Interfacial ionic transport processes are key steps in energy conversion in batteries, fuel cells, supercapacitors and catalysis. To meet the increasing energy demand, high surface/volume ratio materials and devices are developed to enhance the capacity of energy storage and the efficiency of energy conversion. However, fundamental understanding of molecular and ionic tranport processes within confined nanoscale is limited that hinders the technology developments. With geometric-defined nanodevices, frequency domain responses of ionic transport are investigated by impedance methodology, which unprecedently resolve respective bulk and surface contributions.

Illustrated above, the unique current rectification (non-linear Ohmic behavior, conductivity panel on the left) observed from various nanopores and nanochannels, and striking impedance behavior discovered in our group, reveal distinct ionic transport behaviors at nanoscale.

Multidentate thiolate functionalized metal nanoclusters

Materials with nanosized dimension have interesting properties resulted from quantum confinement effects. In the context of small nanoclusters, an appreciable number of core atomes participate in surface bonding, therefore interfacial bond structures significantly impact their composition, structure and properties. The group employs multidentate thiols with designated molecular structures to create novel metal nanoclusters with designed energetics for applications in nanoelectronics, catalysis, biology and medicine.

Selected Publications

1. Wang, G.; Bohaty, A.; Zharov, I. and White, H. S. Photon-Gated Transport at the Glass Nanopore Electrode, J. Am. Chem. Soc. 2006, 128, 13553.
2. Wang, G.; Zhang, B. Wayment, J. R.; Harris, J. M. and White, H. S. Electrostatic-Gated Transport in Chemically Modified Glass Nanopore Electrodes, J. Am. Chem. Soc. 2006, 128, 7679.
3. Wang, G.; Guo, R.; Kalyuzhny, G.; Choi, J.-P. and Murray, R. W. NIR Luminescence Intensities Increase Linearly with Proportion of Polar Thiolate Ligands in Protecting Monolayers of Au38 and Au140 Quantum Dots, J. Phys. Chem. B 2006, 110, 20282.
4. Guo, R.; Song, Y.; Wang, G.; Murray, R. W. Does Core Size Matter in the Kinetics of Ligand Exchanges of Monolayer-Protected Au Clusters? J. Am. Chem. Soc. 2005, 127, 2752.
5. Wang, G.; Huang, T.; Murray, R. W.; Menard, L.; Nuzzo, R. G. Near-IR Luminescence of Monolayer Protected Metal Clusters, J. Am. Chem. Soc. 2005, 127, 812.
6. Lee, D.; Donkers, R. L.; Wang, G.; Harper, A. S. and Murray, R. W. Electrochemistry and Optical absorbance and luminescence of Molecule-like Au38 Nanoparticles. J. Am. Chem. Soc. 2004, 126, 6193.
7. Wang, G. and Murray, R. W. Controlled Assembly of Monolayer-Protected Gold Clusters by Dissolved DNA. Nano Lett. 2004, 4, 95.
8. Zhang, J.; Wang, G.; Shon,Y.-S.; Zhou, O.; Superfine, R. and Murray, R. W. Interactions of Small Molecules and Au Nanoparticles with Solubilized Single-Wall Carbon Nanotubes. J. Phys. Chem. B 2003, 107, 3726.
9. Wang, G.; Zhang, J. and Murray, R. W. DNA binding of an ethidium intercalator attached to a monolayer-protected gold cluster. Anal. Chem. (accelerated article) 2002, 74, 4320.

Patent:
H. S. White; B. Zhang; R. J. White; E. N. Ervin; G. Wang. “Nanopore Electrode, Nanopore Membranes, Methods of Preparation and Surface Modification and Use Thereof” patent filed

Book Chapter:
Bo Zhang, Gangli Wang, and Henry S. White, “Glass nanopore electrodes” in Handbook of Electrochemistry, Cynthia G. Zoski, Ed., Elsevier, in press 2006